Atherogenic lipid risk factors in men classified as overweight and obese according to the preliminary WHO guidelines for Asians.

نویسندگان

  • Hanumanthappa Nandeesha
  • Viswanathan Sathiyapriya
  • Zachariah Bobby
  • Nambiar Selvaraj
  • Purushothaman Pavithran
  • Aparna Agrawal
چکیده

The prevalence of obesi ty is increasing in bo th the deve loped and deve lop ing count r ies , wi th 10–50% of the Ind ian population are being reported as obese (1). Obes i ty i s an impor tan t r i sk fac tor fo r coronary hear t d i sease and i t has been repor ted tha t overweigh t and obes i ty increase the r i sk fo r hosp i ta l i za t ion and death f rom cardiovascular d isease (2) . The increased card iovascular r i sk in obes i ty i s at least partly mediated through atherogenic dys l ip idemia charac te r ized by an increase in p lasma t r ig lycer ides , low dens i ty lipoprotein (LDL) cholesterol as well as low concent ra t ions o f h igh dens i ty (HDL) cholesterol. Defining BMI (body mass index) cu t – off l eve l s a t which adverse cardiovascular outcomes are more l ikely to occur are relevant to patient care. The BMI cut – off levels for Asians d i ffer f rom that of Europeans. There is increasing evidence of a h igh preva lence of type 2 d iabe tes mellitus and cardiovascular disease in Asian countr ies despi te an average BMI < 25 kg/ m in these countries (3). The WHO (World Heal th Oganiza t ion) had pu t fo rward new BMI criteria for Asians based on the report by reg ional off ice for the Western Pac i f ic region of WHO (4). The present study was an attempt to assess the suitability of these new guidel ines for c lassifying Indians into overweigh t and obese based on the i r atherogenic indices of l ipid metabol ism.

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عنوان ژورنال:
  • Indian journal of physiology and pharmacology

دوره 52 2  شماره 

صفحات  -

تاریخ انتشار 2008